Solvent Recycling Size Exclusion Chromatography

Japan Analytical LC-9160 II Next

Synthesis of high added-values molecules is one of the main axis of the Rennes Institute of Chemical Sciences (ISCR). In this context, the separation/purification of these molecules is a major issue. The recycling High Performance Liquid Chromatography (HPLC) is an innovative tool which allows better purifications while diminishing solvent consumption.
This purification system is localised at the Institut des Sciences Chimiques de Rennes - UMR CNRS 6226, Université de Rennes 1, CNRS, Campus de Beaulieu - Bât. 10A, F-35042 Rennes Cedex. It will be under the supervision of Pierre-Antoine Bouit, CNRS Researcher Fellow.
The preparative recycling solvent HPLC uses chloroform as solvent and can make up to 99 successives cycles.
It can separate molecular organic compounds as well as organometallic complexes (150 Da <MW< 1000 Da) up to 300mg of compound on a JAIGEL-2H column.
The detection is made by UV-visible absorption (four detection wavelengths from 190 nm to 840 nm).

Solvent recycling size exclusion chromatography