Jean-Pierre Bazureau

UR1 Full Professor

Jean-Pierre Bazureau

Email : jean-pierre [dot] bazureau [at] univ-rennes1 [dot] fr

Phone : +33 (0) 2 23 23 66 03

Office number : Beaulieu 10A, Office 207

Professional Experience

  • 2002-present: Full Professor - University of Rennes 1, Rennes Institute of Chemical Sciences (ISCR) - UMR CNRS 6226, Rennes, France
  • 1991-2001: Associate Professor - University of Rennes 1, UMR CNRS 6510, Rennes, France
  • 1988-1991: R&D Chemical Engineer and Head of "Applied Sciences Laboratory for Life Sciences" in an US chemical engineering & manufacturing company (Nantes, France)
  • 1987-1988: R&D Chemical Engineer in European company (ZI Saint-Ouen, France)

Education

  • 1997: Habilitation in Chemical Sciences - Organic Chemistry - University of Rennes 1, Rennes, France
  • 1987 Ph.D in Organic Synthesis on "Synthesis of dehydro aminoacides and dipeptides via Wittig reactions" - University of Rennes 1, Rennes, France
  • 1984: Master Sc. in Organic Chemistry - University of Rennes 1, Rennes, France

Research interests

  • "Store Operated Calcium Entry" inhibitors (Orai1) for cancer via Délikine program inhibitors
  • Mitochondrial Ion channel inhibitors for cancer
  • Protein kinase (PKs) inhibitors for CNS (Alzheimers' disease and Down syndrome) via Leucettine program inhibitors
  • Fluorescence probes for studies of molecular mechanisms in cancer biology
  • Microwave assisted organic chemistry and scale-up
  • Chemical tools issued from Ionic Liquids & applied to organic synthesis

Teaching

  • "Building-block strategies & hetero-chemistry" in Master Sc. of Molecular Chemistry, University of Rennes 1, Rennes, France
  • "Advanced courses on analytical techniques of separation (HPLC & GC)" in Master Sc. of Analytical Chemistry
  • "Crop chemistry" in Master Sc. of Plant Biology, University of Rennes 1, Rennes, France
  • "Ionic liquid Chemistry & Microwave Synthesis: from lab to bulk" in International Master Sc. of Catalysis & Molecular Chemistry, University of Rennes 1, Rennes, France
  • Microwave technologies and applications in Organic Synthesis, University Savoie Mont Blanc, Chambéry, France
  • "Microwave technologies applied to organic synthesis and extraction: from lab to bulk", University Nangui-Abrogoua, Abidjan, Côte d'Ivoire

Main Administrative & Collectives Activities

  • 2015-present: Founder and Head of "S2 Wave platform" in ScanMAT UMS 2001 CNRS, University of Rennes 1
  • Member of the Council of the UMR 6226 - Rennes Institute of Chemical Sciences (ISCR) (2012-16)
  • 2007-13: Manager of Master Sc. for Analytical Chemistry, University of Rennes 1
  • 2009-14: Scientific Advisory Board Member of ManRos Therapeutics (Roscoff, France)
  • 2005-12: Member of "CSE, Comité Sélection & d'Expertise" for "Bretagne Valorisation", University of Rennes 1
  • 2015-present: Editorial Advisory Board member of Pharmaceuticals (MDPI)
  • Scientific expert for research and evaluation of national agencies: ANR, HCERES, Regional Councils, Universities,...; and international: EEC, ATHINER, FNRS, ….

Membership of professional organizations

Member of the French Chemical Society (SCF), the Therapeutic Chemical Society (SCT), "Marine molecules, Metabolism and Cancer" network in Cancéropôle Grand-Ouest (CGO), Donor member of the "Fondation Rennes 1"

Ongoing collaborations

  • Prof. Y-A. Békro, Prof. J. Mamyrbékova - University of Nangui Abrogoua UNA, Abidjan, Côte d'Ivoire (2009-present)
  • Dr O. Mignen, Dr C. Brigaudeau - LBAI Inserm U1227, CHU Morvan, University Bretagne Occidentale, Brest, France (2012-present)
  • Prof. H. Ammar, Prof. S. Abid - LCA-HCGP LR01ES22 - University of Sfax, Sfax, Tunisie (2012-present)
  • Dr S. Ruchaud, Dr S. Bach - KISSf platform, Station Biologique CNRS, Roscoff, France (2011-present)
  • Prof. T. Charlier, Dr R. Le Guével - ImPACcell platform, SFR Biosit, Université de Rennes 1 (2011-present)
  • Dr J-F Dumas, Dr M. Guéguinou, Prof. C. Vandier - N2C Inserm U1069, CHU Tours (2017-present)
  • Dr L. Meijer, CEO, Perha Pharmaceuticals, Roscoff, France (2003-present)
  • Dr V. Marchi, DR CNRS & Dr P. Even-Hernandez, ISCR UMR CNRS 6226, Macse group, Université de Rennes 1

Awards

  • Top-50 Tetrahedron Most Cited Paper 2003-2006 Award: 232nd ACS Full National Meeting "Cycle of Excellence", San Francisco (USA), September 10, 2006.
  • Top-50 Tetrahedron Most Cited Paper 2004-2007 Award
  • Thomson Reuters 2003 Award
  • Laureate 2019 of the "Fondation Entreprises Grand Ouest BPO - Territoire de la Recherche" for NanoFluoInCa project

Bioactive Molecular Pipeline

Molecular Pipeline - (1.61 MB)

Amphi High School Students

Amphi Lycéens 2016 - (18.57 MB)

Scientific Production

  • Peer reviewed publications: > 120
  • Invited talks at conferences: 28
  • Oral Communications, Key Notes at Conferences: 68
  • Conferences in Industry: 6
  • Book chapter: 6
  • Patent & "Soleau" envelope: 5
  • Supervisor of Ph D: 19
  • Scientific supervision of Post-Docs: 15

Publications referenced in HAL :