Evidencing octahedral metal cluster red-NIR emission and singlet oxygen generation by two photon absorption

Discovery of a new property in an old family of compounds
Evidencing ((n-C4H9)4N)2[W6I14] red-NIR emission and singlet oxygen generation by two photon absorption

Figure. Irradiating the octahedral metal cluster where biological tissues absorb the less leads to a red NIR emission and to the generation of Reactive Oxygen Species

Known for about 90 years, the two photon absorption (TPA) -induced luminescence is an active area of research in the field of three-dimensional optical data storage, multiphoton emission spectroscopy and microscopy, or photodynamic therapy (PDT). In this last case, materials endowed with TPA-induced phosphorescence are particularly attractive. NIR excitation minimizes tissue autofluorescence and provides a deeper penetration in biological tissues compared to visible light. Besides, singlet oxygen can be produced by energy transfer from the triplet excited state reached by TPA. Hence, such materials are prime candidates for non-invasive therapy.

Thanks to the Caphter platform from UMS ScanMAT who developed a new set-up, researchers from the Rennes Institute of Chemical Sciences (ISCR) in Rennes have evidenced for the first time such properties in a whole family of inorganic molecular compounds made of cheap and non-toxic elements: the octahedral transition metal cluster compounds.

This proof-of-concept work opens new perspectives in the development of innovative tools for bioimaging and non-invasive PDT.

References

  • Evidencing ((n-C4H9)4N)2[W6I14] red-NIR emission and singlet oxygen generation by two photon absorption
    Yann Molard,* Grégory Taupier, Serge Paofai, Stéphane Cordier
    Chemical Communications, 2021, DOI: 10.1039/D1CC00751C
     
  • Expanding the Toolbox of Octahedral Molybdenum Clusters and Nanocomposite Made Thereof: Evidence of Two-Photon Absorption induced -NIR Emission and -Singlet Oxygen Production
    Soumaya Khlifi, Gregory Taupier, Maria Amela-Cortes, Noe Dumait, Stephane Freslon, Stphane Cordier, Yann Molard
    Inorg. Chem. 2021, DOI: 10.1021/acs.inorgchem.1c00517

Contact

Yann Molard - Univ Rennes, CNRS, ISCR - UMR 6226, ScanMAT – UMS 2001, F-35000 Rennes, France
yann [dot] molardatuniv-rennes1 [dot] fr

 

Published March 26, 2021