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UR1 Associate Professor

Maître de Conférences
Institut des Sciences Chimiques de Rennes UMR 6226
Université de Rennes 1
Campus de Beaulieu
35042 Rennes, France
Building 10A, Office 210
Phone: +33 (0)
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Research themes / Technical skills

• Nanoparticles and functional self-assemblies: applications in imagery and therapy.
• Toxicity of Nanoparticles (ANR France/Germany Solnanotox 2014-2017)
• Interactions involving Biomolecules: with biomimetic membranes, nanoparticles, peptides, drugs.
• Bioconjugation and catalysis in water (porphyrins).
• Conformational stability and electron transfer activity of hemoproteins in hydrated ionic liquids: structure-function relationship.
• Spectroscopies (Liquid NMR, CD, FTIR, UV-Visible absorption, Fluorescence emission), Light Scattering (DLS, NTA), Calorimetry (DSC, ITC).

Education and professional experience

• University of Rennes 1, ISCR UMR CNRS 6226, France (2008-), Associate Professor.
• University of Rennes 1, Institut de Génétique et Développement de Rennes, UMR CNRS 6290, France (2008), Research Ingenior.
• University of Florence, Centro di Ricerca di Risonanze Magnetiche, Sesto Fiorentino, Italie, Postdoctoral fellow (janv 2005- oct 2007).
• University of Rennes 1, UMR CNRS 6509, PhD thesis in Structural Biology (2001-2004).

Teaching activities

• Biomolecules and Spectroscopy (M1 of Chemistry, L2 STS PCSTM)
• Atomistic (L1 STS Biology- Environment- Life Chemistry)
• Polymers (ESIR2)
• Informatics (L3 STS)
• Organic Chemistry (L3 STS)

Teaching Responsabilities

• Master 1 of Chemistry: Responsible of the UE 3b “Chemistry of Life” (2017- ) ( 10-20 students)
• L2 of Chemistry : Responsible of the UE Compléments Scientifiques “SVE2” (2017- ) ( 50 students)
• L1 Biology-Environment-Chemistry of Life (BECV) : responsible of the UE3 “ATOM”: atomistic, organic chemistry and solution chemistry (2011- ) (500-600 students)

Committee work

• Elected Member of the ISCR’s board regent (2011-2016)(2017-...)
• Elected Member of the Chemical Section of the UFR SPM (2011-2016)

Scientific Collaborations

Dr Corinne Lagrost, MaCSE, IGDR (France): Direct electrochemistry and elctrocataluysis of hemoproteins in non-conventional Ionic liquid media.
Dr Marie-Bérengère Troadec, GEO, IGDR, (France): development of multi-modal imaging tools for targeting tumors.
Dr Sophie Pinel,Centre de Recherche en, Automatique de Nancy (CRAN), UMR7039 Université de Lorraine-CNRS
Département Santé-Biologie-Signal (SBS) (France): development of tools for a multi-therapy approach.

Scientific Production

Selected publications
• Simple Engineering of Polymer–Nanoparticle Hybrid Nanocapsules
F. Sciortino,G. Casterou, P-A. Eliat,M-B. Troadec, C. Gaillard, S.Chevance,M. L Kahn, and F. Gauffre. ChemNanoMat. 2016, 2, 796-799. doi: 10.1002/cnma.201600155
• Metal-catalyzed asymmetric sulfoxidation, epoxidation and hydroxylation by hydrogen peroxide.
H. Srour, P. Le Maux, S. Chevance and G. Simonneaux (2013). Coord Chem Rev 2013, 270, 3030-3050. doi:10.1016/j.ccr.2013.05.010
• Peptidic Ligands to Control the Three-Dimensional Self-Assembly of Quantum Rods in Aqueous Media T Bizien, P Even-Hernandez.
M Postic, E Mazari, S Chevance, A Bondon, C Hamon, D Troadec, L Largeau, C Dupuis, C Gosse, F Artzner, V Marchi , Small 2011, 18, 3707–3716. doi: 10.1002/smll.201400300
• Direct electron transfer of hemoglobin and myoglobin at the bare glassy carbon electrode in an aqueous BMI.BF4 ionic-liquid mixture.
G Loget, S Chevance, C Poriel, G Simonneaux, C Lagrost, J Rault-Berthelot, ChemPhysChem 2011, 12, 411-418. doi: 10.1002/cphc.201000779.
• Biological and biophysical properties and interaction with recombinat HDAC7 of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) are affected by short alkyl group substitution of the phenyl ring.
F Oger, A Lecorgne, E Sala, S Chevance, D Desravines, P Barath, D Hart, A Bondon, D Carettoni, G Simonneaux, G Salbert, J Med Chem 2010, 53, 1937-1950. doi: 10.1021/jm901561u.
• Cytochrome c and SDS: a molten globule protein with altered axial ligation.
Bertini, P. Turano, P. R. Vasos*, A. Bondon, S Chevance* and G. Simonneaux, J. Mol. Biol. 2004, 336, 489-496. doi:10.1016/j.jmb.2003.12.045. (alphabetical order : two firts authors designed by *)

• dépôt de brevet français « ASSEMBLAGES DE NANOPARTICULES HYDROPHOBES EN MILIEU AQUEUX » n° 15 62860 (18/12/2015), étendu à l’international en décembre 2016. (SATT Ouest Valorisation)

Publications referenced in HAL