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Caroline NUGIER-CHAUVIN

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Caroline NUGIER-CHAUVIN

ENSCR - Assistant Professor

Institut des Sciences Chimiques de Rennes UMR 6226
ENSCR
11 allée de Beaulieu
CS 503837
35708 Rennes cedex 7, France

Building B, Office 118
Phone: +33 (0) 2.23.23.80.66
Email: caroline.nugier@ensc-rennes.fr

Research themes

• Biotechnological processes for the synthesis and the modification of glycofuranosides and glycoconjugates (glycosylhydrolases, lipases, thioglycoligases and mutated enzymes)
• Bioactive molecules (immunomostimulating agents, anti-parasitic drugs, tensioactive agents,…)
• Recovery of renewable raw materials: plant and algal polysaccharides, lipids
• Enzymatic polymerization

Key words / Scientific skills

• Glycochemistry : chemo-enzymatic glycosylation, enzymatic modification of carbohydrates
• Biocatalysis
• Protein engineering mutagenesis, protein over-expression and purification to allow the production of tailored biocatalysts
• Microbiology
• Enzymology

Education and professional experience

• Actual position

  • ➢ (2003-) Assistant Professor
  • ➢ (2011-) Dean of Graduate Academic Affairs at ENSC Rennes

• Post-doctoral fellow (1991-92) Glaxo Group Research in medicinal chemistry department (Greenford-London, UK)
• PhD (1988-91) in Chemical Sciences - Laboratoire de Chimie Organique et des Substances Naturelles de l’ENSC Rennes
• Master Degree in Organic Chemistry (1988) Univ. Rennes I
• French Graduate Chemical Engineer Degree (1988) ENSC Rennes

Teaching activities

Advanced Chemistry and Engineering Degree
Molecular Chemistry Master
• Organic chemistry
• Biological chemistry
• Natural Products
• Biocatalysis
• Metabolic Biochemistry
• Design and supervision of training projects in innovation, research and bibliography

Membership in professional organizations

• Dean of Graduate Academic Affairs at ENSC Rennes (-2011)
• Elected member of the ENSCR Board of Directors (-2012)
• Member of the Education working group of the network Gay-Lussac Federation (FGL)
• Nominated member of the Academic Council and of the Education working group of the ComUE Université Bretagne Loire.

Committee work

• Member of the Groupe Français des Glycosciences (GFG)
• Member of the Club des Bioconversions en Synthèse Organique (CBSO)

Awards

• “Prime d’Encadrement Doctoral et de Recherche“, then “Prime Excellence Scientifique” (-1999).
• Knight in the Order of “Palmes Académiques” (-2015)

Collaborations

• CINVESTAV, Irapuato (Mexique, L. Herrera-Estrella, A.-L. Chauvin)
• ICT Prague (République Tchèque, B. Kralova, V. Spiwok)
• Académie des Sciences Tchèque (République Tchèque, D. Filip)
• Department of Pathology, University of Louisville, USA (Prof. V. Vetvicka)
• Montpellier SupAgro, Département des Sciences pour les Agro-Bioprocédés (Pr. E. Dubreucq)
• Laboratoire de Parasitologie-Mycologie, Univ. Rennes 1, INSERM U522, CHU, Pr Jean-Pierre Gangneux
• INSERM U522, Univ. Rennes 1 Dr Pascal Loyer

Democratization of science

Regular intervention in schools and in science festivals.
Communication and information concerning the Chemistry and Engineering Degree program as well as the undergraduate program for specific admission to the Schools of FGL towards : bachelors, graduate and undergraduate students, high schools pupils.

Scientific Production

• H. Casajus, S. Tranchimand, D. Wolbert, C. Nugier-Chauvin, S. Cammas-Marion, J. Appl. Polym. Sci., 2016, DOI: 10.1002/app.44604.

• A. Pennec, R. Daniellou, P. Loyer, C. Nugier-Chauvin, V. Ferrieres Carbohydr. Res. 2015, 402, 50–55.

• A. Pennec, L. Legentil, L. Herrera-Estrella, V. Ferrières, A.-L. Chauvin, C. Nugier-Chauvin, Green Chem., 2014, 16, 3803-3809.

• I. Chlubnová, B. Sylla, C. Nugier-Chauvin, R. Daniellou, L. Legentil, B. Králová, V. Ferrières Nat. Prod. Rep., 2011, 28, 937-952.

• I. Chlubnová, D. Filipp, V. Spiwok, H. Dvořáková, R. Daniellou, C. Nugier-Chauvin, B. Králová, V. Ferrières Org. Biomol. Chem., 2010, 8, 2092-2102.

Invited talks at Conferences: 3
Communications at Conferences: 32
Seminars in Laboratories: 5
Publications: 54
Book Chapter: 6
Patent: 4

Publications referenced in HAL