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CNRS Director of Research

(Directeur de Recherche CNRS)

Institut des Sciences Chimiques de Rennes UMR 6226
Université de Rennes 1
Campus de Villjean
35043 Rennes, France

Building 5-East, Office 928
Phone: +33 (0)
Click here to send an e-mail

Research themes

• Peptides - lipids interaction
• Antimicrobial mechanism
• Membrane models for NMR ; SUV
• Kinetics of interaction
• Structure determination of antimicrobial peptides and neuropeptides


• Peptides - lipids interaction
• 3D structure
• antimicrobial

Education and professional experience

• Actual position (1988 - ) CNRS researcher; Director since 2007
• Post-doctoral fellow: Department of Biochemistry, Nashville (Tennessee), Pr. F. P. Guengerich (1987 – 1988)
• PhD: Thèse de Doctorat de l’Université de Rennes (1984 - 1987)
• Master Degree: Maîtrise de Biochimie - Diplôme d’Etudes Approfondies Chimie, Rennes (1982 - 1984)

Membership in professional organizations


Committee work


Collaborations industrielles

• Société Microbs, Rennes

Scientific Production

Selected scientific production:
• Sterols associated with Small Unilamellar Vesicles (SUV): intrinsic mobility role for 1H NMR detection.
Mouret L., Da Costa G., Bondon A., Magn. Res. Chem, 2014, 52, 339–344.
• Heterobi- and -trimetallic Ion Pairs of Zirconocene-Based Isoselective Olefin Polymerization Catalysts with AlMe3: First Crystal Structures, Solution Dynamics and C-H Activation Processes.
G. Theurkauff, A. Bondon, V. Dorcet, J-F. Carpentier, E. Kirillov, Angew. Chem. Int. Ed., 2015, 54, 6343-6346.
• Two distinct conformational states of Mycobacterium tuberculosis virulent factor ESAT-6 are behind the controversy around its biological functions.
Refai, A., Haoues M., Othman H., Ridha Barbouche M., Moua P., Bondon A., Mouret L. Srairi-Abid N., Essafi M., FEBS J., 2015, 282, 4114-4129.
• Elucidation by NMR solution of neurotensin in Small Unilamellar Vesicle environment: molecular surveys for neurotensin receptor recognition.
G. Da Costa, A. Bondon, O. Delalande, L. Mouret, J-P. Monti, J. Biomol. Struct. Dyn, 2013, 31, 809-817.
• From a Marine Neuropeptide to Antimicrobial Pseudopeptides including Aza-β3-AminoAcids: Activities and Structures.
M. Laurencin, B. Legrand, E. Duval, J. Henry, M. Baudy-Floc’h, C. Zatylny-Gaudin, A. Bondon, J. Med. Chem., 2012, 55, 2025-2034.

Invited talks at Conferences:
• Modèles membranaires, RMN et peptides.
• ATSB 24ème Forum, Sousse, Tunisie, 25-28 mars 2013.

Publications referenced in HAL